BACKGROUND Hemangiomas are the most common benign tumors of infancy. This study evaluated the efficacy of oral propranolol comparing to oral steroids in management of pediatric hemangiomas. METHODS In North India from January 2012 to January 2015, sixty children <6 years old with superficial hemangiomas were divided into 2 groups; oral propranolol vs. oral prednisolone. All participants we...

purpose: to assess the effect and long-term results of oral propranolol in pediatric capillary hemangiomas. methods: four children aged 3 months to 5 years with periocular and orbital hemangioma of infancy (hoi) were treated with propranolol, 2 milligram per kilogram per day divided in 2 doses. propranolol was continued in all cases until the end of the first year of life and tapered over 2-3 w...

abstract background: prolonged labor can lead to maternal and neonatal complications. the purpose of this study was to investigate the effect of oral propranolol plus oxytocin versus oxytocin only on the process and outcome of labor. materials and methods: in a randomized, double-blind, controlled trial performed in ilam mustafa hospital, a total of 146 nulliparous pregnant women at gestational...

1. Racial differences in propranolol enantiomer kinetics following oral dosing were previously documented in our laboratory. The purpose of this study was to more completely describe propranolol kinetics in black and white subjects with the goal of gaining a better understanding of the mechanism(s) responsible for racial differences in oral propranolol kinetics. 2. Twelve white and 13 black hea...

OBJECTIVES (1) To present six patients with symptomatic airway hemangiomas treated with oral propranolol. (2) To review the diagnostic and treatment options for airway hemangiomas and propose a new management protocol. STUDY DESIGN Retrospective review. SETTING Tertiary care children's hospital. SUBJECTS AND METHODS Pediatric patients diagnosed with obstructive airway hemangiomas treated ...

INTRODUCTION Oral propranolol has improved the treatment of infantile hemangiomas, and a pediatric oral solution of propranolol has recently been licensed in the USA and Europe. In very preterm infants, infantile hemangiomas are associated with the occurrence of retinopathy of prematurity (ROP), and both diseases share a peculiar time course, featuring a lag phase after birth followed by rapid ...

Background: Infantile haemangioma is the commonest childhood tumor. Several lines of treatment are available. Recent reports have focused on the value of propranolol in treating rapidly proliferating haemangioma. The aim of this study was to assess oral propranolol in treatment for facial haemangioma. Patients and Methods: Fifteen patients with rapidly proliferating infantile facial haemangioma...

PURPOSE To investigate the efficacy and safety of oral propranolol in the management of periorbital infantile hemangioma in four subjects. MATERIALS AND METHODS Consecutive patients who presented with periorbital capillary hemangioma with vision-threatening lesions were prospectively enrolled in this study between January 2009 and October 2010. All subjects underwent treatment with 2 mg/kg/da...

The main objectives of the study were to determine the exposure and bioavailability of oral propranolol and to investigate their associations with serum bile acid concentration in patients with liver cirrhosis and in healthy controls. A further objective was to study the pharmacodynamics of propranolol. An open-label crossover study was performed to determine the pharmacokinetics and pharmacody...

Oral propranolol is a nonselective betablocker that could play a relevant role in exudative control of retinal hemangioblastomae, as during oral propranolol treatment the size of the lesion remained stable and exudative activity was entirely inhibited. The relapse exhibited by the patient during the months in which he discontinued propranolol treatment gave rise to its reintroduction. Since the...